Tuesday, February 24, 2015

How to Develop New Antibiotics - NYTimes.com

The bacteria are winning.

Every year, according to the Centers for Disease Control and Prevention, at least two million people are infected with bacteria that can't be wiped out with antibiotics, and as a result, 23,000 people die. Direct health care costs from these illnesses are estimated to be as high as $20 billion annually.

Just last week, the U.C.L.A. Health System announced that nearly 180 patients may have been exposed to the CRE superbug that was linked to two deaths in one of its hospitals. Today, 30 percent of severe strep pneumonia infections are resistant to multiple drugs and 30 percent of gonorrheainfections are resistant to all antibiotics. And drug-resistant enterobacteriaceae, enterococcus, acinetobacter and a slew of other unpronounceable bacteria pose serious threats.

The development of antibiotics has been glacial. We need a completely new approach.

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